AGBL1

Across TCGA pan-cancer cohorts, AGBL1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of AGBL1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where AGBL1 RNA is repressed in tumor relative to normal tissue. In most cancer types AGBL1 is over-expressed in tumor, although a few such as LUAD and HNSC show the opposite, repressed pattern.

LUAD, HNSC, and LUSC are the cancer types where AGBL1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AGBL1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	−0.904	<.001	9	view →
HNSC	Male	All	−1.359	<.001	8	view →
LUSC	Female	All	−0.777	<.001	7	view →
KIRC	All	All	+0.180	.010	6	view →
COAD	All	II,III,IV	−0.019	.003	3	view →
PRAD	All	All	−0.110	.030	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

AGBL1–LUAD

Open the LUAD breakdown →