AGBL1

Across TCGA cell cohorts, AGBL1 mutation is significantly associated with the RNA expression of many other genes, with 472 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AGBL1-associated genes across cancer lineages are CEP76, GAR1, and DHX15. Each is linked with AGBL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGBL1-to-partner and partner-to-AGBL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CEP76 grouped by AGBL1-low versus AGBL1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGBL1→partner) and Y-score (partner→AGBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CEP76 →	+0.533	+1.949	.005	.002	3	2
LARGE_INTESTINE	GAR1 →	+0.523	+2.350	<.001	.008	3	2
LARGE_INTESTINE	DHX15 →	+0.405	+2.459	.003	.006	3	2
LARGE_INTESTINE	DDX6 →	+0.403	+2.526	.005	.002	3	2
LARGE_INTESTINE	STAG1 →	+0.562	+1.949	<.001	.002	3	2
LARGE_INTESTINE	NAPG →	+0.530	+1.949	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 472 associations by consensus.

CEP76 by AGBL1 expression — LARGE_INTESTINE

Explore this box plot interactively →