AGAP5

Across TCGA patient cohorts, AGAP5 mutation is significantly associated with the RNA expression of many other genes, with 545 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AGAP5-associated genes across cancer lineages are LINC01809, LINC01849, and RN7SL680P. Each is linked with AGAP5 in more than 2 cancer types. Because this analysis shows association rather than direction, both AGAP5-to-partner and partner-to-AGAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01809 grouped by AGAP5-low versus AGAP5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP5→partner) and Y-score (partner→AGAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC01809 →	+0.113	+3.458	<.001	.004	3	3
STAD	LINC01849 →	+0.265	+3.828	.006	.009	3	3
SKCM	RN7SL680P →	+0.112	+4.219	<.001	.006	3	2
STAD	RNU6-1078P →	+0.488	+4.267	<.001	.003	3	2
BRCA	RNU6-278P →	+0.232	+7.731	<.001	.009	3	2
HNSC	MIR378D1 →	+0.461	+7.954	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 545 associations by consensus.

LINC01809 by AGAP5 expression — SKCM

Explore this box plot interactively →