AGAP5

Across TCGA pan-cancer cohorts, AGAP5 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of AGAP5’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where AGAP5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types AGAP5 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

STAD, THCA, and KIRC are the cancer types where AGAP5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AGAP5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.234	.003	6	view →
THCA	All	All	−0.129	<.001	6	view →
KIRC	Male	All	+0.113	<.001	6	view →
COAD	Male	II,III,IV	+0.122	.004	4	view →
LIHC	Female	All	+0.092	<.001	4	view →
KICH	All	All	−0.105	.004	3	view →
CHOL	All	All	+0.442	.004	2	view →
READ	All	All	+0.226	.024	2	view →
KIRP	All	IV	+0.162	.001	2	view →
HNSC	All	All	+0.036	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

AGAP5–STAD

Open the STAD breakdown →