AGAP5

Across TCGA cell cohorts, AGAP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,818 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible AGAP5-associated GO terms across cancer lineages are Base-excision repair, gap-filling, Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Regulation of mRNA splicing, via spliceosome. Each is linked with AGAP5 in more than 16 cancer types. Because this analysis shows association rather than direction, both AGAP5-to-partner and partner-to-AGAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Base-excision repair, gap-filling grouped by AGAP5-low versus AGAP5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP5→partner) and Y-score (partner→AGAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Base-excision repair, gap-filling →	+0.118	+0.734	<.001	.003	3	17
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.162	+1.214	<.001	<.001	3	17
BONE	Regulation of mRNA splicing, via spliceosome →	+0.102	+1.119	<.001	<.001	3	17
SOFT_TISSUE	Microtubule nucleation →	+0.136	+1.116	<.001	<.001	3	17
BONE	Negative regulation of translational initiation →	+0.119	+1.216	<.001	<.001	3	16
OESOPHAGUS	Viral translational termination-reinitiation →	+0.101	+1.113	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,818 associations by consensus.

Base-excision repair, gap-filling by AGAP5 expression — OESOPHAGUS

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