Across TCGA patient cohorts, AGAP4 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,939 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AGAP4-associated proteins across cancer lineages are GATAD2B, GMPPA, and DHX9. Each is linked with AGAP4 in more than 5 cancer types. Because this analysis shows association rather than direction, both AGAP4-to-partner and partner-to-AGAP4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP4→partner) and Y-score (partner→AGAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GATAD2B →	+0.315	+0.599	<.001	<.001	3	6
GBM	GMPPA →	-0.321	-0.472	<.001	<.001	3	5
GBM	DHX9 →	+0.185	+0.423	.001	<.001	3	5
HNSC	HNRNPLL →	+0.247	+0.424	.002	.007	3	5
GBM	NRF1 →	+0.283	+0.356	.002	.003	3	4
GBM	OGT →	+0.237	+0.439	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,939 associations by consensus.

Exploration

AGAP4 survival (RNA) · tumor vs normal (RNA) · all AGAP4 data types