Across TCGA pan-cancer cohorts, AGAP4 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated AGAP4 data layer compared with 5 for mutation status.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher AGAP4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated AGAP4 expression acts as an unfavorable survival marker, although some lineages such as BLCA and HNSC show a favorable association.
ACC, KIRC, and LIHC are the cancer types where AGAP4 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.