Across TCGA patient cohorts, AGAP4 mutation is significantly associated with the RNA expression of many other genes, with 769 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGAP4-associated genes across cancer lineages are MIR5697, MTHFD2P5, and MIR6826. Each is linked with AGAP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGAP4-to-partner and partner-to-AGAP4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP4→partner) and Y-score (partner→AGAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR5697 →	+0.541	+4.299	.005	.007	3	2
HNSC	MTHFD2P5 →	+0.061	+4.952	<.001	.002	3	2
HNSC	MIR6826 →	+0.382	+4.197	.004	.009	3	2
UCEC	RBM17P1 →	+0.036	+3.186	<.001	.001	3	2
BRCA	RNA5SP169 →	+0.192	+7.471	<.001	.008	3	1
BRCA	EIF2S2P7 →	+0.058	+5.721	.007	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 769 associations by consensus.

Exploration

AGAP4 survival (RNA) · tumor vs normal (RNA) · all AGAP4 data types