Across TCGA cell cohorts, AGAP4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible AGAP4-associated genes across cancer lineages are PSKH2, OR7G2, and OR2L5. Each is linked with AGAP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGAP4-to-partner and partner-to-AGAP4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP4→partner) and Y-score (partner→AGAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PSKH2 →	+0.024	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR7G2 →	+0.018	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR2L5 →	+0.012	+4.887	.001	.009	3	1
LUNG_NSCLC_LUAD	TXNDC8 →	+0.006	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

AGAP4 survival (RNA) · tumor vs normal (RNA) · all AGAP4 data types