Across TCGA cell cohorts, AGAP4 mutation is significantly associated with the mutation status of many other genes, with 86 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible AGAP4-associated genes across cancer lineages are ZNF491, OR2G6, and OR52K1. Each is linked with AGAP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGAP4-to-partner and partner-to-AGAP4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP4→partner) and Y-score (partner→AGAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ZNF491 →	+5.772	+5.772	.002	.002	1	2
LUNG_NSCLC_LUAD	OR2G6 →	+4.772	+5.339	.004	.004	1	1
LUNG_NSCLC_LUAD	OR52K1 →	+4.772	+5.339	.004	.004	1	1
LUNG_NSCLC_LUAD	LCE1C →	+4.772	+5.339	.004	.004	1	1
LUNG_NSCLC_LUAD	OR8B8 →	+4.772	+5.339	.004	.004	1	1
LUNG_NSCLC_LUAD	TTC37 →	+4.187	+5.000	.008	.008	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

Exploration

AGAP4 survival (RNA) · tumor vs normal (RNA) · all AGAP4 data types