AGAP12P

Across TCGA patient cohorts, AGAP12P mutation is significantly associated with the RNA expression of many other genes, with 2,257 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGAP12P-associated genes across cancer lineages are LINC00294, TCAIM, and VWA1. Each is linked with AGAP12P in more than 1 cancer types. Because this analysis shows association rather than direction, both AGAP12P-to-partner and partner-to-AGAP12P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00294 grouped by AGAP12P-low versus AGAP12P-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP12P→partner) and Y-score (partner→AGAP12P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC00294 →	+0.481	+2.176	.002	.002	3	2
SKCM	TCAIM →	+0.516	+1.822	<.001	.007	3	2
UCEC	VWA1 →	-1.112	-2.652	<.001	<.001	3	2
SKCM	MEX3D →	+0.657	+1.797	<.001	.008	3	2
UCEC	LSM10 →	+0.303	+2.595	.007	.005	3	2
SKCM	SKA2 →	+0.605	+3.484	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,257 associations by consensus.

LINC00294 by AGAP12P expression — SKCM

Explore this box plot interactively →