AGAP12P

Across TCGA pan-cancer cohorts, AGAP12P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of AGAP12P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where AGAP12P RNA is repressed in tumor relative to normal tissue. In most cancer types AGAP12P is over-expressed in tumor, although a few such as BRCA and LUAD show the opposite, repressed pattern.

BRCA, PAAD, and KIRC are the cancer types where AGAP12P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AGAP12P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.252	.004	6	view →
PAAD	Male	All	+0.909	.046	2	view →
KIRC	All	All	+0.247	<.001	2	view →
LUAD	Male	II,III,IV	−0.187	.043	1	view →
LIHC	All	All	+0.105	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

AGAP12P–BRCA

Open the BRCA breakdown →