AGAP11

Across TCGA pan-cancer cohorts, AGAP11 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated AGAP11 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher AGAP11 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated AGAP11 expression acts as an unfavorable survival marker, although some lineages such as UCS and BLCA show a favorable association.

UCS, BLCA, and DLBC are the cancer types where AGAP11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	III,IV	0.504	0.140	.002	60	view →
BLCA	OS	Tertile	All	0.773	0.631	.001	54	view →
DLBC	DFS	Tertile	III,IV	0.074	0.984	.003	48	view →
UVM	DFS	Quartile	All	0.109	0.903	<.001	40	view →
LIHC	OS	Tertile	III,IV	0.773	0.552	.011	30	view →
LUSC	OS	Tertile	III,IV	0.652	0.317	.015	22	view →
HNSC	OS	Tertile	IV	0.612	0.376	.016	20	view →
THYM	DFS	Median	All	1.000	0.678	.004	19	view →
BRCA	DFS	Tertile	III,IV	0.858	0.726	.012	17	view →
COAD	OS	Median	IV	0.841	0.435	.004	17	view →
THCA	OS	Quartile	II,III,IV	0.604	0.948	.009	15	view →
ESCA	OS	Quartile	All	0.849	0.635	.020	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

AGAP11–UCS (DFS)

Open the UCS breakdown →