AGAP11

Across TCGA pan-cancer cohorts, AGAP11 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of AGAP11’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where AGAP11 RNA is repressed in tumor relative to normal tissue. In most cancer types AGAP11 is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LUAD, KICH, and KIRC are the cancer types where AGAP11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AGAP11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	−0.401	<.001	9	view →
KICH	All	All	−0.250	<.001	8	view →
KIRC	All	All	+0.184	<.001	7	view →
BRCA	All	III,IV	−0.804	<.001	6	view →
LUSC	Female	II,III,IV	−0.492	<.001	6	view →
UCEC	All	All	−0.463	<.001	6	view →
COAD	All	III,IV	−0.079	.005	5	view →
THCA	Female	All	−0.144	.001	4	view →
STAD	All	All	−0.197	.007	3	view →
ESCA	All	II,III,IV	−0.424	.015	2	view →
READ	All	III,IV	+0.175	.028	2	view →
CHOL	All	All	+0.105	.007	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

AGAP11–LUAD

Open the LUAD breakdown →