AGAP1

Across TCGA cell cohorts, AGAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,975 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AGAP1-associated GO terms across cancer lineages are Regulation of modification of postsynaptic structure, Regulation of modification of synaptic structure, and Phosphatidylinositol biosynthetic process. Each is linked with AGAP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both AGAP1-to-partner and partner-to-AGAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of modification of postsynaptic structure grouped by AGAP1-low versus AGAP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP1→partner) and Y-score (partner→AGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of modification of postsynaptic structure →	+0.163	+0.981	<.001	<.001	3	17
OVARY	Regulation of modification of synaptic structure →	+0.117	+1.234	<.001	<.001	3	16
SKIN	Phosphatidylinositol biosynthetic process →	+0.067	+1.091	<.001	<.001	3	12
BONE	Transcription pausing by RNA polymerase II →	+0.109	+0.925	.009	<.001	3	12
BONE	Mitotic sister chromatid separation →	+0.162	+0.949	.004	.002	3	12
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.062	+1.080	.003	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,975 associations by consensus.

Regulation of modification of postsynaptic structure by AGAP1 expression — BONE

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