Across TCGA patient cohorts, AFG3L1P mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AFG3L1P-associated genes across cancer lineages are A-Raf_pS299, MEK1, and Annexin-1. Each is linked with AFG3L1P in more than 1 cancer types. Because this analysis shows association rather than direction, both AFG3L1P-to-partner and partner-to-AFG3L1P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AFG3L1P→partner) and Y-score (partner→AFG3L1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.162	-3.321	.003	.010	3	1
UCEC	MEK1 →	+0.471	+3.459	.005	.005	3	1
UCEC	Annexin-1 →	+0.891	+3.189	<.001	.010	3	1
UCEC	AR →	-0.424	-2.584	.014	.011	3	1
UCEC	TFRC →	+0.800	+3.169	.001	.018	3	1
UCEC	TIGAR →	+0.150	+2.611	.034	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

AFG3L1P survival (RNA) · tumor vs normal (RNA) · all AFG3L1P data types