AEBP2

Across TCGA patient cohorts, AEBP2 mutation is significantly associated with the RNA expression of many other genes, with 835 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AEBP2-associated genes across cancer lineages are OPALIN, SNORD115-46, and MIR6894. Each is linked with AEBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AEBP2-to-partner and partner-to-AEBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPALIN grouped by AEBP2-low versus AEBP2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AEBP2→partner) and Y-score (partner→AEBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OPALIN →	+0.028	+4.621	.001	.004	3	2
BRCA	SNORD115-46 →	+0.456	+7.467	<.001	<.001	3	1
BRCA	MIR6894 →	+0.367	+4.506	<.001	.009	3	1
SKCM	LINC01221 →	+0.186	+5.224	<.001	.007	3	1
BRCA	RNU6-1299P →	+0.323	+4.721	<.001	.007	3	1
BRCA	MIR2114 →	+0.424	+5.215	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 835 associations by consensus.

OPALIN by AEBP2 expression — BRCA

Explore this box plot interactively →