AEBP1

Across TCGA patient cohorts, AEBP1 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AEBP1-associated genes across cancer lineages are ATM, Caspase-7-cleavedD198, and mTOR_pS2448. Each is linked with AEBP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both AEBP1-to-partner and partner-to-AEBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by AEBP1-low versus AEBP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AEBP1→partner) and Y-score (partner→AEBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.471	-2.571	.001	.010	3	4
COAD	Caspase-7-cleavedD198 →	+1.466	+3.178	<.001	.010	3	3
LUAD	mTOR_pS2448 →	-0.177	-3.000	.036	.034	3	2
LUAD	CD20 →	+0.168	+2.824	.014	.034	3	2
LUAD	Chk1 →	+0.218	+2.584	.030	.011	3	2
STAD	ERK2 →	+0.414	+3.000	.009	.036	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

ATM by AEBP1 expression — UCEC

Explore this box plot interactively →