AEBP1

Across TCGA pan-cancer cohorts, AEBP1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated AEBP1 data layer compared with 5 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher AEBP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated AEBP1 expression acts as an unfavorable survival marker, although some lineages such as THYM and DLBC show a favorable association.

KIRP, LGG, and MESO are the cancer types where AEBP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	II,III,IV	0.339	0.705	<.001	109	view →
LGG	DFS	Median	All	0.650	0.822	<.001	54	view →
MESO	OS	Tertile	II,III,IV	0.177	0.380	.009	30	view →
BLCA	OS	Quartile	All	0.320	0.640	.002	25	view →
ACC	OS	Quartile	All	0.414	0.913	.001	24	view →
GBM	OS	Quartile	All	0.203	0.367	.001	23	view →
STAD	OS	Median	All	0.521	0.638	.012	20	view →
THYM	OS	Median	All	1.000	0.709	<.001	19	view →
HNSC	DFS	Median	All	0.549	0.768	<.001	17	view →
DLBC	DFS	Tertile	All	0.781	0.311	.014	17	view →
ESCA	DFS	Median	II,III,IV	0.494	0.266	.015	13	view →
CHOL	DFS	Median	All	0.600	0.259	.029	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

AEBP1–KIRP (OS)

Open the KIRP breakdown →