AEBP1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, AEBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,485 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AEBP1-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Protein-DNA complex organization, and Establishment of RNA localization. Each is linked with AEBP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both AEBP1-to-partner and partner-to-AEBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by AEBP1-low versus AEBP1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AEBP1→partner) and Y-score (partner→AEBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTNegative regulation of syncytium formation by plasma membrane fusion →+0.155+2.319<.001.003311
LUNG_SCLCProtein-DNA complex organization →+0.065+2.218.001<.001311
LUNG_SCLCEstablishment of RNA localization →+0.106+2.262<.001<.001311
UPPER_AERODIGESTIVE_TRACTRegulation of protein localization to Cajal body →+0.083+2.215.001.007310
UPPER_AERODIGESTIVE_TRACTPositive regulation of protein localization to Cajal body →+0.083+2.215.001.007310
UPPER_AERODIGESTIVE_TRACTTranscription initiation at RNA polymerase II promoter →+0.070+2.115.001.009211
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,485 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by AEBP1 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Negative regulation of syncytium formation by plasma membrane fusion in AEBP1-low vs AEBP1-high samples in UPPER_AERODIGESTIVE_TRACT.

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Exploration