AEBP1

Across TCGA cell cohorts, AEBP1 mutation is significantly associated with the RNA expression of many other genes, with 988 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AEBP1-associated genes across cancer lineages are CDC7, CEP76, and BLOC1S6. Each is linked with AEBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AEBP1-to-partner and partner-to-AEBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDC7 grouped by AEBP1-low versus AEBP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AEBP1→partner) and Y-score (partner→AEBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CDC7 →	+0.711	+3.120	.005	.009	3	2
LARGE_INTESTINE	CEP76 →	+0.669	+2.265	<.001	.001	3	2
LARGE_INTESTINE	BLOC1S6 →	+0.392	+3.321	.005	.003	3	2
LARGE_INTESTINE	BCAT2 →	+0.578	+3.169	<.001	.006	3	2
LARGE_INTESTINE	BCL7A →	+0.687	+2.459	.003	.006	3	2
LARGE_INTESTINE	C12orf57 →	+0.829	+2.265	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 988 associations by consensus.

CDC7 by AEBP1 expression — BLOOD_Leukemia

Explore this box plot interactively →