Across TCGA cell cohorts, ADSS1 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADSS1-associated genes across cancer lineages are IL9, SIGLECL1, and BPIFB6. Each is linked with ADSS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADSS1-to-partner and partner-to-ADSS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADSS1→partner) and Y-score (partner→ADSS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	IL9 →	+0.053	+5.781	<.001	.001	3	1
BREAST	SIGLECL1 →	+0.026	+5.781	<.001	.001	3	1
LARGE_INTESTINE	BPIFB6 →	+0.020	+4.437	<.001	.004	3	1
LARGE_INTESTINE	OR2AT4 →	+0.018	+4.196	.001	.002	3	1
LARGE_INTESTINE	OR2J3 →	+0.044	+3.920	<.001	.005	3	1
LARGE_INTESTINE	OR2J1 →	+0.004	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

ADSS1 survival (RNA) · tumor vs normal (RNA) · all ADSS1 data types