ADRM1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADRM1 mutation is significantly associated with the RNA expression of many other genes, with 674 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADRM1-associated genes across cancer lineages are RN7SL97P, OR7E10P, and MTND5P35. Each is linked with ADRM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADRM1-to-partner and partner-to-ADRM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL97P grouped by ADRM1-low versus ADRM1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRM1→partner) and Y-score (partner→ADRM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL97P →+0.156+5.144<.001.00332
CESCOR7E10P →+0.048+5.144<.001.00332
CESCMTND5P35 →+0.021+4.539<.001.00832
SKCMMIR1205 →+0.530+4.241.003.00832
BLCARPS3AP30 →+0.067+3.506<.001.00532
UCECTRAJ49 →+0.796+2.081<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 674 associations by consensus.

RN7SL97P by ADRM1 expression — CESC

Box plot of RN7SL97P in ADRM1-low vs ADRM1-high samples in CESC.

Explore this box plot interactively →

Exploration