ADRM1

Across TCGA pan-cancer cohorts, ADRM1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ADRM1 data layer compared with 3 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ADRM1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ADRM1 expression acts as an unfavorable survival marker, although some lineages such as READ and ESCA show a favorable association.

KIRC, KIRP, and KICH are the cancer types where ADRM1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.829	0.911	<.001	152	view →
KIRP	DFS	Median	All	0.854	0.958	<.001	89	view →
KICH	OS	Median	II,III,IV	0.602	1.000	.002	77	view →
BLCA	DFS	Median	III,IV	0.468	0.624	<.001	67	view →
MESO	OS	Median	II,III,IV	0.291	0.495	.002	65	view →
ACC	DFS	Median	All	0.284	0.638	<.001	48	view →
LIHC	OS	Tertile	All	0.571	0.754	<.001	47	view →
LGG	DFS	Median	All	0.650	0.827	<.001	40	view →
LUSC	DFS	Quartile	III,IV	0.213	0.991	.001	28	view →
UCEC	DFS	Median	All	0.859	0.930	.008	16	view →
READ	DFS	Tertile	IV	0.889	0.366	.011	15	view →
BRCA	OS	Quartile	II,III,IV	0.856	0.927	.016	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ADRM1–KIRC (DFS)

Open the KIRC breakdown →