ADRB1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADRB1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,822 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADRB1-associated genes across cancer lineages are UPB1, CYTH4, and MFNG. Each is linked with ADRB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADRB1-to-partner and partner-to-ADRB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADRB1 versus UPB1 in LSCC, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRB1→partner) and Y-score (partner→ADRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCUPB1 →+0.353+1.262.008.00131
LSCCCYTH4 →+0.940+0.833.009.00131
LSCCMFNG →+1.222+0.806<.001.00231
LSCCAPOBEC3H →+1.421+1.311.004.00431
LSCCFOXRED2 →-0.870-0.763.002.00431
LSCCNCF4 →+1.024+0.833.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,822 associations by consensus.

ADRB1 vs UPB1 — LSCC

Per-sample scatter of ADRB1 vs UPB1 in LSCC (Pearson r = 0.76).

Explore this scatter interactively →

Exploration