Across TCGA patient cohorts, ADRA2C RNA expression is significantly associated with the protein abundance of many other proteins, with 13,928 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADRA2C-associated proteins across cancer lineages are TTC7B, DAB2IP, and EIF5B. Each is linked with ADRA2C in more than 4 cancer types. Because this analysis shows association rather than direction, both ADRA2C-to-partner and partner-to-ADRA2C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRA2C→partner) and Y-score (partner→ADRA2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TTC7B →	+0.386	+0.523	<.001	<.001	3	4
GBM	DAB2IP →	+0.336	+0.849	<.001	<.001	3	4
LUAD	EIF5B →	-0.199	-0.562	<.001	<.001	3	4
UCEC	EML1 →	+0.417	+1.147	.008	.003	3	4
CCRCC	LCP2 →	-0.396	-1.095	<.001	<.001	3	4
LUAD	PLEKHA6 →	+0.409	+0.608	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,928 associations by consensus.

Exploration

ADRA2C survival (RNA) · tumor vs normal (RNA) · all ADRA2C data types