Across TCGA cell cohorts, ADRA2C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,931 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ADRA2C-associated GO terms across cancer lineages are Blood coagulation, intrinsic pathway, Regulation of potassium ion transport, and Negative regulation of norepinephrine secretion. Each is linked with ADRA2C in more than 10 cancer types. Because this analysis shows association rather than direction, both ADRA2C-to-partner and partner-to-ADRA2C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRA2C→partner) and Y-score (partner→ADRA2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Blood coagulation, intrinsic pathway →	-0.238	-1.246	<.001	<.001	3	11
LIVER	Regulation of potassium ion transport →	-0.147	-2.151	.001	<.001	3	11
LIVER	Negative regulation of norepinephrine secretion →	+1.321	+3.275	.005	<.001	3	11
BREAST	Tertiary alcohol biosynthetic process →	+1.523	+2.140	<.001	<.001	3	11
BREAST	Cortisol biosynthetic process →	+1.523	+2.140	<.001	<.001	3	11
OVARY	Positive regulation of DNA repair →	+0.067	+1.532	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,931 associations by consensus.

Exploration

ADRA2C survival (RNA) · tumor vs normal (RNA) · all ADRA2C data types