ADRA2A

Across TCGA patient cohorts, ADRA2A RNA expression is significantly associated with the protein abundance of many other proteins, with 15,928 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ADRA2A-associated proteins across cancer lineages are ADRA2A_S346, SEPTIN4, and ADH1B. Each is linked with ADRA2A in more than 9 cancer types. Because this analysis shows association rather than direction, both ADRA2A-to-partner and partner-to-ADRA2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADRA2A versus ADRA2A_S346 in LSCC, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRA2A→partner) and Y-score (partner→ADRA2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ADRA2A_S346 →	+1.387	+0.902	<.001	<.001	3	10
PDAC	SEPTIN4 →	+0.452	+0.830	.004	.004	3	6
OV	ADH1B →	+2.050	+1.495	<.001	<.001	3	6
OV	CNRIP1 →	+0.699	+1.511	<.001	<.001	3	6
BRCA	HAAO →	+0.517	+1.513	.001	<.001	3	6
OV	SGCD →	+0.665	+1.261	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,928 associations by consensus.

ADRA2A vs ADRA2A_S346 — LSCC

Explore this scatter interactively →