ADRA1B

Across TCGA patient cohorts, ADRA1B protein abundance is significantly associated with the RNA expression of many other genes, with 348 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADRA1B-associated genes across cancer lineages are BIK, PNPLA3, and MCF2. Each is linked with ADRA1B in more than 1 cancer types. Because this analysis shows association rather than direction, both ADRA1B-to-partner and partner-to-ADRA1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADRA1B versus BIK in GBM, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRA1B→partner) and Y-score (partner→ADRA1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BIK →	-0.611	-1.001	.005	<.001	3	1
GBM	PNPLA3 →	-1.807	-1.175	<.001	<.001	3	1
GBM	MCF2 →	+0.825	+0.681	.001	<.001	3	1
GBM	GPR50 →	+0.081	+0.806	.003	<.001	3	1
GBM	PBDC1 →	-0.485	-0.774	<.001	.001	3	1
GBM	HMOX2 →	+0.524	+0.826	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 348 associations by consensus.

ADRA1B vs BIK — GBM

Explore this scatter interactively →