ADRA1B

Across TCGA cell cohorts, ADRA1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,259 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ADRA1B-associated GO terms across cancer lineages are Adenylate cyclase-activating adrenergic receptor signaling pathway, Biological process involved in symbiotic interaction, and Caveola assembly. Each is linked with ADRA1B in more than 11 cancer types. Because this analysis shows association rather than direction, both ADRA1B-to-partner and partner-to-ADRA1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adenylate cyclase-activating adrenergic receptor signaling pathway grouped by ADRA1B-low versus ADRA1B-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRA1B→partner) and Y-score (partner→ADRA1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Adenylate cyclase-activating adrenergic receptor signaling pathway →	-0.172	-1.259	<.001	.002	2	12
UPPER_AERODIGESTIVE_TRACT	Biological process involved in symbiotic interaction →	+0.090	+1.229	.002	.001	3	11
LIVER	Caveola assembly →	+0.322	+1.587	<.001	<.001	3	11
BONE	Positive regulation of cytoskeleton organization →	+0.089	+1.598	<.001	<.001	3	11
LIVER	Wound healing →	+0.115	+1.638	.003	<.001	3	11
BONE	Regulation of plasma membrane repair →	+0.284	+0.952	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,259 associations by consensus.

Adenylate cyclase-activating adrenergic receptor signaling pathway by ADRA1B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →