ADRA1A

Across TCGA cell cohorts, ADRA1A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,919 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADRA1A-associated GO terms across cancer lineages are Cytoplasmic translation, NADH dehydrogenase complex assembly, and Mitochondrial respiratory chain complex I assembly. Each is linked with ADRA1A in more than 4 cancer types. Because this analysis shows association rather than direction, both ADRA1A-to-partner and partner-to-ADRA1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by ADRA1A-low versus ADRA1A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRA1A→partner) and Y-score (partner→ADRA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cytoplasmic translation →	+0.069	+0.247	<.001	.007	3	5
BONE	NADH dehydrogenase complex assembly →	+0.097	+1.727	.001	.003	3	5
BONE	Mitochondrial respiratory chain complex I assembly →	+0.097	+1.727	.001	.003	3	5
BONE	Negative regulation of smooth muscle cell apoptotic process →	+0.099	+1.756	.002	.009	3	5
BONE	Protein-RNA complex organization →	+0.088	+1.562	<.001	<.001	3	5
BONE	Nucleoside triphosphate biosynthetic process →	+0.077	+1.351	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,919 associations by consensus.

Cytoplasmic translation by ADRA1A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →