ADPRS

Across TCGA cell cohorts, ADPRS RNA expression is significantly associated with the go_rna of many other GO terms, with 3,629 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADPRS-associated GO terms across cancer lineages are RISC complex assembly, Spindle midzone assembly, and Nucleoside diphosphate metabolic process. Each is linked with ADPRS in more than 13 cancer types. Because this analysis shows association rather than direction, both ADPRS-to-partner and partner-to-ADPRS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RISC complex assembly grouped by ADPRS-low versus ADPRS-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADPRS→partner) and Y-score (partner→ADPRS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RISC complex assembly →	+0.127	+0.760	<.001	<.001	3	14
BREAST	Spindle midzone assembly →	+0.175	+0.715	<.001	<.001	3	12
BREAST	Nucleoside diphosphate metabolic process →	+0.078	+0.648	.006	.002	3	11
URINARY_TRACT	Positive regulation of autophagy of mitochondrion →	+0.105	+0.825	.008	.001	3	11
LIVER	ADP catabolic process →	+0.121	+0.666	.003	.004	3	11
STOMACH	Positive regulation of mitophagy →	+0.102	+0.691	<.001	.003	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,629 associations by consensus.

RISC complex assembly by ADPRS expression — BONE

Explore this box plot interactively →