ADPRM

Across TCGA cell cohorts, ADPRM mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADPRM-associated genes across cancer lineages are ASB17, C12orf40, and GUCA1C. Each is linked with ADPRM in more than 1 cancer types. Because this analysis shows association rather than direction, both ADPRM-to-partner and partner-to-ADPRM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by ADPRM-low versus ADPRM-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADPRM→partner) and Y-score (partner→ADPRM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	1
OVARY	C12orf40 →	+0.011	+4.029	<.001	.009	3	1
LARGE_INTESTINE	GUCA1C →	+0.123	+4.095	.008	.009	3	1
LARGE_INTESTINE	KCTD8 →	+0.188	+4.095	.002	.009	3	1
LARGE_INTESTINE	TBC1D3 →	+0.080	+4.273	<.001	.006	3	1
LARGE_INTESTINE	GSC2 →	+0.168	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

ASB17 by ADPRM expression — OVARY

Explore this box plot interactively →