ADPRHL1

Across TCGA patient cohorts, ADPRHL1 mutation is significantly associated with the RNA expression of many other genes, with 902 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADPRHL1-associated genes across cancer lineages are RNU6-1175P, CASKP1, and RN7SL654P. Each is linked with ADPRHL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADPRHL1-to-partner and partner-to-ADPRHL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1175P grouped by ADPRHL1-low versus ADPRHL1-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADPRHL1→partner) and Y-score (partner→ADPRHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	RNU6-1175P →	+0.283	+7.977	<.001	.007	3	3
SKCM	CASKP1 →	+0.045	+2.902	<.001	.003	3	2
SKCM	RN7SL654P →	+0.035	+4.225	<.001	.005	3	2
LUSC	IGKV2D-23 →	+0.278	+4.192	<.001	.003	3	2
LUSC	CYP4F36P →	+0.161	+4.393	.002	.008	3	2
SKCM	SOD1 →	+0.436	+3.341	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 902 associations by consensus.

RNU6-1175P by ADPRHL1 expression — LGG

Explore this box plot interactively →