ADPRH

Across TCGA pan-cancer cohorts, ADPRH mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ADPRH data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ADPRH mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ADPRH expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

COAD, GBM, and CCRCC are the cancer types where ADPRH mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.901	1.000	.019	24	view →
GBM	DFS	Tertile	All	0.189	0.489	<.001	15	view →
CCRCC	DFS	Median	All	0.524	1.000	.001	10	view →
HNSC	DFS	Quartile	All	0.912	1.000	.024	6	view →
PDAC	OS	Median	II,III,IV	0.947	0.727	.029	3	view →
LSCC	DFS	Tertile	III,IV	0.536	1.000	.024	1	view →
LUAD	DFS	Quartile	All	0.759	0.493	.033	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ADPRH–COAD (DFS)

Open the COAD breakdown →