ADPRH

Across TCGA patient cohorts, ADPRH mutation is significantly associated with the RNA expression of many other genes, with 1,645 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADPRH-associated genes across cancer lineages are FOXN3P1, RNU6-566P, and SPTY2D1. Each is linked with ADPRH in more than 2 cancer types. Because this analysis shows association rather than direction, both ADPRH-to-partner and partner-to-ADPRH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXN3P1 grouped by ADPRH-low versus ADPRH-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADPRH→partner) and Y-score (partner→ADPRH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FOXN3P1 →	+0.046	+4.209	.001	.001	3	3
HNSC	RNU6-566P →	+0.348	+7.954	<.001	.008	3	2
UCEC	SPTY2D1 →	+0.488	+2.156	.006	.009	3	2
UCEC	KIFBP →	+0.485	+3.280	.006	<.001	3	2
UCEC	RP9P →	+0.611	+2.606	<.001	<.001	3	2
UCEC	IGHD3-9 →	+1.139	+2.535	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,645 associations by consensus.

FOXN3P1 by ADPRH expression — LUAD

Explore this box plot interactively →