ADPRH

Across TCGA cell cohorts, ADPRH mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADPRH-associated genes across cancer lineages are LGALS16, NKX2-6, and TLE7. Each is linked with ADPRH in more than 1 cancer types. Because this analysis shows association rather than direction, both ADPRH-to-partner and partner-to-ADPRH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LGALS16 grouped by ADPRH-low versus ADPRH-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADPRH→partner) and Y-score (partner→ADPRH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LGALS16 →	+0.060	+5.228	<.001	.005	3	1
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

LGALS16 by ADPRH expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →