ADPGK-AS1

Across TCGA pan-cancer cohorts, ADPGK-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ADPGK-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ADPGK-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ADPGK-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, LUSC, and ACC are the cancer types where ADPGK-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	III,IV	0.490	0.256	<.001	122	view →
LUSC	DFS	Tertile	II,III,IV	0.520	0.896	.003	61	view →
ACC	OS	Median	All	0.442	0.811	<.001	60	view →
UVM	OS	Median	III,IV	0.296	1.000	.005	48	view →
THCA	OS	Median	II,III,IV	0.959	0.992	.004	37	view →
LUAD	OS	Quartile	II,III,IV	0.449	0.268	.007	31	view →
LGG	DFS	Quartile	All	0.344	0.530	<.001	31	view →
CESC	DFS	Quartile	All	0.811	0.618	.005	28	view →
BRCA	OS	Tertile	III,IV	0.935	0.862	.011	21	view →
READ	OS	Median	II,III,IV	0.911	0.460	.003	16	view →
PAAD	OS	Median	II,III,IV	0.681	0.489	.001	12	view →
GBM	DFS	Tertile	All	0.186	0.401	.011	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

ADPGK-AS1–HNSC (OS)

Open the HNSC breakdown →