ADPGK-AS1

Across TCGA pan-cancer cohorts, ADPGK-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ADPGK-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ADPGK-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ADPGK-AS1 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

KIRC, HNSC, and STAD are the cancer types where ADPGK-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ADPGK-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.212	<.001	11	view →
HNSC	Female	II,III,IV	+0.106	<.001	10	view →
STAD	All	All	+0.172	<.001	7	view →
KIRP	All	All	+0.141	<.001	7	view →
LUSC	Female	All	−0.342	<.001	6	view →
LUAD	All	III,IV	−0.194	.004	6	view →
PAAD	All	All	−0.307	.004	2	view →
UCEC	All	III,IV	+0.144	.038	2	view →
THCA	Male	II,III,IV	+0.094	.011	2	view →
CHOL	All	All	+0.097	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

ADPGK-AS1–KIRC

Open the KIRC breakdown →