ADNP

Across TCGA patient cohorts, ADNP protein abundance is significantly associated with the RNA expression of many other genes, with 20,503 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADNP-associated genes across cancer lineages are RAE1, NELFCD, and CSE1L. Each is linked with ADNP in more than 9 cancer types. Because this analysis shows association rather than direction, both ADNP-to-partner and partner-to-ADNP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADNP versus RAE1 in COAD, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADNP→partner) and Y-score (partner→ADNP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RAE1 →	+0.810	+0.308	<.001	<.001	3	10
COAD	NELFCD →	+0.796	+0.341	<.001	<.001	3	10
HNSC	CSE1L →	+0.927	+0.382	.002	<.001	3	10
OV	ILF3 →	+0.859	+0.264	<.001	.008	3	10
HNSC	CSTF1 →	+0.747	+0.430	<.001	<.001	3	9
COAD	MTG2 →	+0.633	+0.285	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,503 associations by consensus.

ADNP vs RAE1 — COAD

Explore this scatter interactively →