Across TCGA patient cohorts, ADM5 mutation is significantly associated with the RNA expression of many other genes, with 61 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADM5-associated genes across cancer lineages are MIR1179, RNU6-830P, and LINC02348. Each is linked with ADM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADM5-to-partner and partner-to-ADM5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADM5→partner) and Y-score (partner→ADM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR1179 →	+1.171	+7.741	<.001	.009	3	2
BRCA	RNU6-830P →	+0.252	+8.471	<.001	.005	3	1
UCEC	LINC02348 →	+0.622	+3.778	<.001	.006	3	1
UCEC	MIR6876 →	+0.984	+3.488	<.001	.008	3	1
UCEC	RPS29P32 →	+1.054	+4.599	<.001	<.001	3	1
UCEC	SSMEM1 →	+0.387	+3.808	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

Exploration

ADM5 survival (RNA) · tumor vs normal (RNA) · all ADM5 data types