Across TCGA cell cohorts, ADM5 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADM5-associated genes across cancer lineages are OR13G1, SLC32A1, and IRX4. Each is linked with ADM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADM5-to-partner and partner-to-ADM5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADM5→partner) and Y-score (partner→ADM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR13G1 →	+0.032	+5.415	<.001	.004	3	1
BLOOD_Leukemia	SLC32A1 →	+0.558	+3.901	.001	.006	3	1
BLOOD_Leukemia	IRX4 →	+0.177	+4.469	<.001	.001	3	1
BLOOD_Leukemia	VRTN →	+0.029	+4.339	.006	.002	3	1
BLOOD_Leukemia	C16orf92 →	+0.139	+4.037	.001	.004	3	1
BLOOD_Leukemia	OR10Q1 →	+0.019	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

ADM5 survival (RNA) · tumor vs normal (RNA) · all ADM5 data types