ADM

Across TCGA pan-cancer cohorts, ADM mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ADM data layer compared with 27 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ADM mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ADM expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC, PDAC, and LUAD are the cancer types where ADM mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	II,III,IV	1.000	0.327	<.001	31	view →
PDAC	DFS	Median	All	0.348	0.873	.022	6	view →
LUAD	OS	Quartile	II,III,IV	0.371	0.919	.040	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ADM–LSCC (DFS)

Open the LSCC breakdown →