ADM

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADM RNA expression is significantly associated with the protein abundance of many other proteins, with 19,778 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADM-associated proteins across cancer lineages are CCN1, PADI4, and PGK1. Each is linked with ADM in more than 6 cancer types. Because this analysis shows association rather than direction, both ADM-to-partner and partner-to-ADM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADM versus CCN1 in COAD, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADM→partner) and Y-score (partner→ADM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCCN1 →+0.715+0.751<.001<.00137
COADPADI4 →+1.014+1.008<.001<.00137
PDACPGK1 →+0.402+0.948.003.00237
BRCALDHA →+0.542+1.699<.001<.00137
GBMLOX →+0.789+1.524<.001<.00137
PDACLOXL2 →+1.088+1.694<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,778 associations by consensus.

ADM vs CCN1 — COAD

Per-sample scatter of ADM vs CCN1 in COAD (Pearson r = 0.42).

Explore this scatter interactively →

Exploration