ADIRF

Across TCGA patient cohorts, ADIRF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,556 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible ADIRF-associated GO terms across cancer lineages are Regulation of cilium assembly, Morphogenesis of a polarized epithelium, and Intraciliary retrograde transport. Each is linked with ADIRF in more than 6 cancer types. Because this analysis shows association rather than direction, both ADIRF-to-partner and partner-to-ADIRF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cilium assembly grouped by ADIRF-low versus ADIRF-high in LGG.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADIRF→partner) and Y-score (partner→ADIRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	Regulation of cilium assembly →	+0.029	+0.005	<.001	.002	3	7
KIRP	Morphogenesis of a polarized epithelium →	+0.025	+0.025	<.001	<.001	3	7
LGG	Intraciliary retrograde transport →	+0.043	+0.004	.001	.004	3	7
STAD	Intraciliary transport →	+0.057	+0.004	.002	.003	2	7
KIRP	Golgi vesicle transport →	+0.026	+0.024	.001	<.001	3	6
MESO	Golgi vesicle budding →	+0.075	+0.020	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,556 associations by consensus.

Regulation of cilium assembly by ADIRF expression — LGG

Explore this box plot interactively →