ADIRF

Across TCGA patient cohorts, ADIRF protein abundance is significantly associated with the RNA expression of many other genes, with 15,759 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ADIRF-associated genes across cancer lineages are SNCG, MMRN2, and AGAP11. Each is linked with ADIRF in more than 7 cancer types. Because this analysis shows association rather than direction, both ADIRF-to-partner and partner-to-ADIRF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADIRF versus SNCG in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADIRF→partner) and Y-score (partner→ADIRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNCG →	+2.132	+1.358	<.001	<.001	3	8
OV	MMRN2 →	+0.895	+1.141	.003	<.001	3	8
CCRCC	AGAP11 →	+0.321	+0.747	<.001	<.001	3	8
OV	TACC3 →	-0.838	-1.022	.002	.002	3	7
BRCA	PLAC9 →	+1.010	+0.905	.002	.001	3	7
CCRCC	GPIHBP1 →	+1.625	+1.066	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,759 associations by consensus.

ADIRF vs SNCG — BRCA

Explore this scatter interactively →