ADIRF

Across TCGA patient cohorts, ADIRF mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADIRF-associated genes across cancer lineages are MEP and Macrophages M2. Each is linked with ADIRF in more than 1 cancer types. Because this analysis shows association rather than direction, both ADIRF-to-partner and partner-to-ADIRF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEP grouped by ADIRF-low versus ADIRF-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADIRF→partner) and Y-score (partner→ADIRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEP →	+0.027	+3.032	.048	.018	3	1
UCEC	Macrophages M2 →	+0.013	+2.831	.012	.035	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MEP by ADIRF expression — UCEC

Explore this box plot interactively →