ADIRF

Across TCGA cell cohorts, ADIRF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,060 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ADIRF-associated GO terms across cancer lineages are Regulation of hippocampal neuron apoptotic process, Negative regulation of hippocampal neuron apoptotic process, and Positive regulation of iron ion transport. Each is linked with ADIRF in more than 10 cancer types. Because this analysis shows association rather than direction, both ADIRF-to-partner and partner-to-ADIRF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hippocampal neuron apoptotic process grouped by ADIRF-low versus ADIRF-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADIRF→partner) and Y-score (partner→ADIRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of hippocampal neuron apoptotic process →	+1.793	+5.357	<.001	<.001	3	11
URINARY_TRACT	Negative regulation of hippocampal neuron apoptotic process →	+1.684	+5.357	<.001	<.001	3	11
URINARY_TRACT	Positive regulation of iron ion transport →	+1.604	+4.579	<.001	<.001	3	11
URINARY_TRACT	Positive regulation of iron ion transmembrane transport →	+1.604	+4.579	<.001	<.001	3	11
STOMACH	Intracellular sodium ion homeostasis →	+0.232	+3.423	.001	.001	3	10
OVARY	Positive regulation of sodium ion transmembrane transport →	+0.270	+2.465	<.001	.005	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,060 associations by consensus.

Regulation of hippocampal neuron apoptotic process by ADIRF expression — URINARY_TRACT

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