ADIPOR2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADIPOR2 mutation is significantly associated with the RNA expression of many other genes, with 2,145 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADIPOR2-associated genes across cancer lineages are RN7SL248P, RN7SL303P, and RNU6-693P. Each is linked with ADIPOR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADIPOR2-to-partner and partner-to-ADIPOR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by ADIPOR2-low versus ADIPOR2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADIPOR2→partner) and Y-score (partner→ADIPOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARN7SL248P →+0.139+6.786<.001<.00133
COADRN7SL303P →+0.904+5.602<.001.00432
COADRNU6-693P →+1.117+6.721<.001<.00132
UCECRNA5SP436 →+0.260+2.800<.001<.00132
BRCALINC02824 →+0.069+5.441.009.00531
COADOR52L1 →+0.265+5.017<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,145 associations by consensus.

RN7SL248P by ADIPOR2 expression — BRCA

Box plot of RN7SL248P in ADIPOR2-low vs ADIPOR2-high samples in BRCA.

Explore this box plot interactively →

Exploration