ADIPOR1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ADIPOR1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADIPOR1-associated genes across cancer lineages are MMP26, C14orf180, and GCGR. Each is linked with ADIPOR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADIPOR1-to-partner and partner-to-ADIPOR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by ADIPOR1-low versus ADIPOR1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADIPOR1→partner) and Y-score (partner→ADIPOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEMMP26 →+0.032+3.632<.001.00331
LARGE_INTESTINEC14orf180 →+0.117+3.155<.001.00831
LARGE_INTESTINEGCGR →+0.177+3.584<.001.00621
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MMP26 by ADIPOR1 expression — LARGE_INTESTINE

Box plot of MMP26 in ADIPOR1-low vs ADIPOR1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration